Bahmanyar Lab in the News: How the Cell Repairs Rips in DNA’s Protective Membrane

All DNA is sealed within the cell’s nuclear membrane, which protects it from molecular marauders. But what happens when that protective envelope rips? Yale researchers tracked the repair process in developing embryos of the worm C. elegans.

In cells with membranes damaged by lasers or disease mutations, a family of proteins act like carpenters to reseal the breach. The Yale team found that the structural scaffold of the nuclear membrane helps the repair of the breach during the healing process, they report Jan. 31 in the journal Molecular Biology of the Cell.

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