| Research Faculty & Dept | Project Title |
| Arnsten, Amy (Neuroscience) |
The M1 Muscarinic Receptor as a Potential Therapeutic Target for Schizophrenia |
| Bahmanyar, Shirin (MCDB) |
Examining Nuclear Envelope Rupture and Repair in Caenorhabditis elegans Embryos |
| Bazell, Robert (MCDB) |
The Molecular Mechanisms of Pembrolizumab, a Cancer Drug that Targets the Disease Based on its Genetic Profile and not the Tissue of Origin with Context from a Review of Cancer Immunotherapy |
| Ben Mamoun, Choukri (Infectious Diseases) |
Targeting Pantotherate Phosphorylation for Development of New Antimaloral and Antifungal Therapies The Role of Pantothenate Kinase 1 and 2 in Pantothenate Metabolism and Malana Pathogenesis and Transmission in Plasmedium Falciparum |
| Bender, Jeffrey (Immunobiology) |
Posttranscriptional Control of Microglia-Derived Neurotrophic Factors |
| Bergwitz, Clemens (Endocrinology) |
Exploring the Effects of Renal Sodium-Phosphate Cotransporters on the Endocrine Regulation of Phosphate Homeostasis |
| Bindra, Ranjit (Therapeutic Radiology) |
Characterization of Poly (ADP-Ribose) Polymerase inhibitors: PARP Trapping Capability and Therapeutic Utility |
| Bordey, Angelique (Neuroscience) |
Examining the Role of Exosomes on Neuronal Morphology in the Context of TSC Disease Role of HCN Ion Channels in Epilepsy |
| Braddock, Demetrios (Pathology) |
Therapeutic Effects of Subcutaneous NPP1 Delivery in Mouse Model of Generalized Arterial |
| Breaker, Ronald (MCDB) |
Characterization of the DNA/RNA Binding Properties of EARO Type B Protein by EMSA Analysis of a Sam Riboswitch Candidate in Streptomyces Determining the Role of a Conserved Bacterial Noncoding RNA in Stress Response Discovery of Novel Non-Coding RNA Structure Genetic Screen of Magnesium-Resistant B Halodurons to Provide Insight into the Function of Ole RNA. |
| Cafferty, William (Neurology) |
Inpp5K Stimulates CNS Axon Growth and Enhances Functional Recovery after Stroke |
| Callender, Glenda (Endocrinology) |
Effect of Preoperative Medical Blockage on Perioperative Hemodynamic Parameters in Patients with Pheochromocytoma |
| Cantley, Lloyd (Nephrology) |
Chasing a Tail: Examining the Localization of the Cleaved C-Terminus of Polycystin-1 The Effect of Oxygen Concentration on Upc2 Expression in ADPKD |
| Carling, Tobias (Endocrinology) |
Molecular Genetics of Adrenocortical Tumorigenesis |
| Chang, William (Nephrology) |
Investigation of Interactions Between Human Endothelial Cells and Renal Glomeruli |
| Colon-Ramos, Daniel (Cell Biology) |
Transforming Sensation into Behavior: Examining the Regulation of C. elegans Temperature Preference and Thermotaxis Behavior The Role of ATG-4.2 in Autophagy in Neurons |
| Crews, Craig (MCDB) |
Development of Protac Against Pseudo Kinases Development of Small Molecule Prothls Targeting the Inhibitor of Apoptosis Protein Investigation into the Effect of P53 Upregulation on Anti-Cancer Efficacy of Bet-Targeting |
| DeLanerolle, Nihal (Neurogsurgery) |
Neurobiology of Hyperthermic Seizures in Rats |
| DiMaio, Daniel (Genetics) |
Cellular Uptake of HPV L2-Fusion Proteins Mapping the Molecular Basis for Interactions between Simple Artificial Proteins and the Erythropoietin Receptor Understanding the Mechanism Through Which Class II Transmembrane Protein Aptamers Inhibit CCR5 Expression |
| Dimitrova, Nadya (MCDB) |
Investigating the Role of LNCRNA-RAPT1 in the P53 Tumor Suppressor Pathway |
| Dominguez-Villar, Margarita (Neurology) |
Investigating the Metabolic Pathway Differences between Tregs and Th1-Like Tregs |
| Eisenbarth, Stephanie (Immunology) |
Investigating the Role of DOCK8 in LGA Production The Role of Toll-Like Receptor 4 and Dedicator of Cytokinesis 8 in LGE Production During Allergic Sensitization in C3H/He5 Mice |
| Hoffman, Ellen (CSC) |
Investigation of Scn1 Lab and Other ASD-Risk Gene Mutant Zebrafish |
| Emonet, Thierry (MCDB) |
Parametric Complexities and Bacterial Strategies in an Agarose Sea of Aspostate |
| Fikrig, Erol (Infectious Disease) |
Agonists of Rev-Erb 2/B Inhibit Viral Replication Identification of Mosquito Salivary Proteins that Impact the Pathogenicity of Zika Virus Investigating the Sufficiency of Select Acdes Acgypti Salivary Protein Anticrums for Protection of Zika Virus-infected Mice and the Mechanisms by Which Protection is Delivered Investigation of Mosquito GILT Saliva Protein in the Inhibition of Plasmodium Transmission The Tick Gut Microbiota and its Effects on Pathogen Transmission |
| Flannery, Clare (OBGYN) |
Characterizing the Molecular and Cellular Relationship between Gestational Diabetes, Mellitus, Obesity and Fetal Outcomes |
| Flavell, Richard (Immunobiology) |
Defining the Translation Potential of Unannotated Protein Coding Genes in the Innate Immune Response |
| Galvani, Alison (Epidemiology) |
Dynamic Model Predictions of Carbapenem Resistance in Response to Antibiotic Sparing Interventions |
| Gendron, Joshua (MCDB) |
Pharmaceutical Molecular Pharming Studying how F-Box Protein Degradation Couples the Plant Circadian Clock to Post Translational Pal Regulation and Further Downstream Processes |
| Goodman, Andrew (Microbial Pathogenesis) |
How the Gut Microbiome Affects the Effectiveness of Cancer Immunotherapy Treatments and the Role of the Gut Microbiota in this Process |
| Gorelick, Fred (Digestive Diseases) |
Zinc-Mediated Attenuation of Caerulein-Induced Pancreatitis |
| Greer, Charles (Neurosurgery) |
Embryonic Development of the Mouse Olfactory Tubercle Investigating the Role of Microglia in Directing Neural Precursor Cells in the Rostral Migratory Stream |
| Grutzendler, Jaime (Neurology) |
Expansion Microscopy Optimization |
| Hatzios, Stavroula (MCDB) |
Strain Dependent Secretion of a Bacterial Serine Protease Active in Cholera |
| Higley, Michael (Neuroscience) |
Analysis of Gephyrin and Gaba a Receptor Interaction on Regions of Neocortical Pyramidal Cells Arousal Associated Activity in Cortical Interneurons |
| Hirschi, Karen (Genetics) |
Connexin 43 Regulates Neural Stem Cell Behavior within the Sub Ventricular Zone of the Brain Via Gap Junctions with Neighboring Endothelial Cells |
| Hoffman, Ellen (CSC) |
Investigating the Function of Scallab in Zebrafish Mutants |
| Horsley, Valerie (MCDB) |
Examining the Role of Reddi in Adipocyte Differentiation |
| Hudnall, S. David (Pathology) |
Role of Human Herpesvirus 6 (Hhv6) in Human Disease |
| Isaacs, Farren (MCDB) |
Developing a Fully Orthogonal Translation System to Accommodate Non-Proteogenic Monomers at the Ribosome Implementing Multiplex Adapted Genome Engineering in Rhizobia The Geobacter Sulfer-Reducens Type IV Pilus: Expression, Structure and Unique Applications of Electrically Conductive Pili Proteins |
| Jacob, Yannick (MCDB) |
Biological Tools for Plant Biology Using Temperature-Optimized Crisp/C09 Gene Editing at the Lyc2 in Chns for Altered Lycopene Levels Precise Engineering of Plant Genomes Using Heat-Activated Retrotransposons Role of Histone H3 Mutations in the Development of Pediatric Gliomas |
| Khokha, Mustafa (Genetics) |
The Spatial and Temporal Characterization of Ciliary Transition Zone Proteins during Cilia Regeneration in MCCS |
| Kibbey, Richard (Endocrinology) |
Regulation of Insulin Secretions through Pep Synthesis Observed Effects of Edopic Pepck-C Expression in Rat Ins-1 832/13 Cells |
| Kliman, Harvey (OBGYN) |
The Role of Serotonin in Colon Cancer Growth |
| Koleske, Anthony (MB&B) |
Investigating the Role of Triple Functional Protein in Neuropsychiatric Disorders |
| Krause, Diane (Cell Bio/Pathology) |
Structure-Function Analysis of Mkl1 in Megakaryopoiesis |
| Kriegel, Martin (Immunobiology) |
Ameliorating Autoimmunity through Diet-Microbiota-Host Immune System Interactions |
| Kyriakides, Themis (Pathology) |
Bulk Metallic Glass as a Bone Implant |
| Lin, Chenxiang (Cell Biology) |
DNA Origami Fluorescent Standard for Tirf |
| Lin, Haifan (Cell Biology) |
Cloning of Miwi2 and Interactors Dnmt3L and DNAj-a1 for Insect Cell Expression Transcriptional Regulation by Material Hpia Is Essential for Drosophila Embryogenesis |
| Lindenbach, Brett (Microbial Pathogenesis) |
Bacterial Effector Proteins as a Toolkit to Study Viral Replication |
| Lu, Lingeng (Epidemiology) |
Weight Loss intervention in Breast Cancer Survivors: Predicting Recurrence Risks using Three Biomarkers |
| MacMicking, John (Microbial Pathogenesis) |
Crispr/Cas9 Interrogation of IFN-Mediated Defense Networks against Bacterial Infection |
| Mani, Arya (Genetics) |
Role of DYRK B in Insulin Resistance |
| Medzhitov, Ruslan (Immunobiology) |
Responses to Bitter Components in the GI Tract Zinc Finger Proteins and Transcriptional Repression in Macrophages |
| Melia, Thomas (Cell Biology) |
Post Translational Regulation of Lc3 Proteins During Autophagy |
| Mooseker, Mark (MCDB) |
Beta-Catenin and E-Cadherin Regulators of Epithelial-Mesenchymal Transition and Cancer Metastasis |
| Nelson, Kenneth (MCDB) |
The Specific Nature of antibodies Allows them to Bind to Targets that may be Specific to Cancer Cells |
| Nguyen, Don (Pathology) |
Targeting Endoplasmic Reticulum Stress Responses in Lung Adenocarcinoma |
| Paintsil, Elijah (Infectious Disease) |
Regulation within Dyx2 Locus |
| Palm, Noah (Immunobiology) |
Nanobody Targeting of Lactobacillus |
| Pollard, Thomas (MCDB) |
Arp2 Phosphorylation is Not Essential for ARP213 Complex Activity The Role of the Sin Pathway in Cytokinesis |
| Pyle, Anna (MCDB) |
Biosynthetic Engineering of the 6-Deoxyerythronolide B Synthase Pathway for Novel Natural Product Synthesis Use of Antisense Oligonucleotides (ASOS) in Treating Lung Cancer by Binding to Different Targets Implicated in Lung Cancer, Such as Insulin-Like Growth Factor I Receptor and Sigma Receptor |
| Rodeheffer, Matthew (Comp Medicine) |
How Genetics and Sex Interact to Influence Obesity and Diabetes |
| Rothlin, Carla (Immunobiology) |
Tam RTK Signaling in Glial Biology |
| Rothman, James (Cell Biology) |
Characterization of the Na-acetyltransferease Naa60 and a Novel Role for Aberrant Acetylation in Familial Basal Ganglia Calcification |
| Schatz, David (Immunobiology) |
Gfp-Based Reporter Assay to Detect Apobec Activity |
| Simon, Matthew (MB&B) |
Deciphering the Structure of incRNA Noradin Vivo Use of Carbodiimide Reagents for the Chemical Probing of RNA Structure |
| Strittmatter, Stephen (Neurology) |
Determining aßo and Pyk2 Regulation of Tau Poly-5 Inhibition of PCP for Rescue of Synaptic Deficits in Transgenic Alzheimer’s Disease Mice |
| Sutton, Richard (Infectious Disease) |
Exploring Transcriptional Regulation of Ccr5 in HIV Elite Controllers |
| Taylor, Hugh (OBGYN) |
Effects of MicroRNAs on Liver Genes that are Involved in Endometriosis |
| Tomayko, Mary (Pathology) |
The Role of Bmpr1a in Differentiation and Survival of Germinal Center B Cells |
| Toomre, Derek (Cell Biology) |
Inpp5E and Pi(4,5)P2 Signaling at the Primary Cilium |
| van Wolfswinkel, Josien (MCDB) |
DNA Methylation in Major Depressive Disorder and Schizophrenia |
| Wajapeyee, Narendra (Pathology) |
Sex Differences in DNA Repair Mechanisms |
| Weinberger, Daniel (Epidemiology) |
Environmental Adaptation of Streptococcus Pneumonia and the Effect on Virulence |
| Wyman, Robert (MCDB) |
Applications of CatSper in Male Contraception |
| Wysolmerski, John (Endocrinology) |
The Role of PTHrP Secretion in Lipolysis and Tumor Cachexia |
| Yang, Xiaoyong (Comp Medicine) |
Identifying Synthetic Genetic Interactions with Perturbed O-Gicnacyation in Pdac Via Genome-Wide Crispr Screen |
| Zenisek, David (C&M Physiology) |
Determining the Effect of Ribeye’s Two Variants on Neuromast Regeneration and Synaptic Ribbon Assembly |
| Zhao, Hongyu (Genetics) |
Hierarchical Bayesian Model Identifies Risk Genes in Congenital Heart Disease |