Undergraduate Research Opportunities

Opportunities will be shared here as they become available.

Research Associate/Technician - Dana-Farber Cancer Institute/HHMI/Harvard Medical School/Broad Institute 

Kadoch Laboratory - Chromatin and gene regulation in human disease 

The Kadoch Laboratory at the Dana-Farber Cancer Institute, Harvard Medical School, the Broad Institute and Howard Hughes Medical Institute (HHMI) is seeking a highly qualified post-baccalaureate student to join our vibrant research team as a Research Associate focused on cancer biology, epigenetics, and chromatin regulation. Our lab uses multidisciplinary approaches including biochemistry, biophysics, structural biology, chemical biology, epigenomics and others to explore the mechanisms of chromatin remodeling complexes, which are frequently mutated in human cancers and other diseases. Our exciting and diverse set of projects involve collaborations across the Harvard and MIT centers in Boston and Cambridge as well as world-wide. This is a highly unique opportunity with potential for the student to work directly with the PI as well as senior postdoctoral fellows, graduate students, and medical students to carry forward independent projects resulting in authorship on publications and opportunities to present work at local, national, and international meetings. This position is ideal for students aiming to pursue either PhD, MD, or combined MD/PhD programs as their next steps. 

The successful applicant will have advanced experience in one or more of the following areas: molecular biology, cell culture and model systems, protein biochemistry, structural biology, cell biology, genetics and/or genomics-centered methodologies, through focused prior lab research experience (i.e. 1-2 years in research laboratories with strong letters of recommendation) as well as undergraduate coursework. We are looking for candidates who can commit to two (2) years of availability, graduating from colleges/universities this Spring 2026 and considering applying to top-tier graduate and/or medical school (PhD/MD/MD-PhD) programs following their tenure in the lab. To date, all postbac research associate lab members in this position have gone on to pursue PhD, MD, or MD/PhD programs at highest-tier institutions. Dr. Kadoch is firmly committed to mentorship, career guidance and support, and other senior lab personnel will also provide consistent research and career mentorship. The ideal candidate will be exceptionally motivated, highly communicative, mature, detail- and goal-oriented, able to work both independently and in teams, and will possess excellent organizational, communication, and analytical skills. 

Please contact Cigall Kadoch, Ph.D., directly at cigall_kadoch@dfci.harvard.edu for more information if interested (along with CV/resume), and please copy Dr. Kadoch’s assistant, Ms. Kristen Applegate, at kadochoffice@gmail.com. We will hire for this position(s) on a rolling basis over the coming months with target start date of May-July 2026, and will close the position once new hires have been confirmed. 

For more information about our laboratory, please see the (to be updated) Kadoch Lab website at http://www.kadochlab.org , our recent publications (https://www.ncbi.nlm.nih.gov/pubmed/?term=kadoch+c), and news via our X handles, @kadochlab, and @ckadoch. 

Computational Biologist Position - Dana-Farber Cancer Institute/HHMI/Harvard Medical School/Broad Institute 

Kadoch Laboratory - Chromatin and gene regulation in human disease 

The Kadoch Laboratory at the Dana-Farber Cancer Institute, Harvard Medical School, Broad Institute, and Howard Hughes Medical Institute is seeking a highly qualified individual who has recently obtained or is about to obtain a BA/BS degree to join our vibrant research team as a Computational Biologist focused on cancer biology, epigenetics, and chromatin regulation. Our lab uses multidisciplinary approaches including biochemistry, biophysics, structural biology, chemical biology, and functional genomics, epigenomics, and AI-based approaches to explore the mechanisms of chromatin remodeling complexes, which are among the most frequently mutated cellular entities in human cancers and other diseases. As such, our computationally centered projects in the lab are highly diverse and involve extensive genomics (i.e. analysis of diverse sequencing methods including DNA-sequencing, RNA-sequencing (RNA-seq), ATAC-seq, ChIP-seq, CUT&RUN, CUT&TAG, single-cell ATAC+RNA-seq, among other approaches), analysis of functional screening datasets (i.e. genome-wide as well as targeted CRISPR- and base editing-based screens for cell fitness or other cellular outcomes), 3D structural biology (i.e. use of Pymol, UCSF Chimera for structural analysis, mapping mutations, etc.), analysis and integration of mass-spectrometry proteomics datasets, and artificial intelligence/machine learning (AI/ML) and systems-biology-focused efforts (i.e. large genomics and proteomics dataset analysis and integration, Deep Mind Alphafold, Rosetta, other approaches). Our exciting collection of ongoing projects involve collaborations with laboratories across the Harvard and MIT research centers, hospitals in Boston and Cambridge, as well as with groups across the country and internationally. This is a unique opportunity with significant potential for the student to work directly with the PI as well as with senior postdoctoral fellows, graduate students and medical students. In addition to working as part of a team(s), the student will carry forward independent projects resulting in authorship on publications and opportunities to present work at local, national, and international meetings. 

The successful applicant will have coding experience (i.e. in R, Python, or other languages) relevant to computational biology/bioinformatics, familiarity with working in a Unix environment and use of SLURM or similar job scheduler (high performance computing and computing clusters), working knowledge of genomic technologies and bioinformatic processes and/or structural biology, ability to both implement and develop new bioinformatic pipelines in shell scripts, interest and proven abilities in data visualization (such as in ggplot2, matplotlib, D3.js etc.), and proficiency in documenting research processes to ensure reproducibility (e.g., markdown syntax and Git/GitHub) as well as experience in one or more of the following areas: computational biology/computer science, molecular biology, genetics and/or genomics, cell biology, and protein biochemistry and/or structural biology, through focused prior dry or wet lab research experience (i.e. 1-2 years in research laboratories with strong letters of recommendation) as well as undergraduate coursework. 

We are looking for candidates who will be available for two years in the lab; in particular, we are looking for candidates who are graduating from colleges/universities this Spring 2026 and considering applying to top-tier graduate and/or medical school (PhD/MD/MD-PhD) programs following their tenure in the lab, *OR*, aiming to function as a senior staff computational biologist in the academic setting for years to come. To date, all postbac computational biology lab members in this position have gone on to pursue PhD, MD, or MD/PhD programs at highest-tier institutions; Dr. Kadoch is firmly committed to mentorship, career guidance and support, and other senior lab personnel will also provide consistent research and career mentorship. The ideal candidate will be exceptionally motivated, highly communicative, mature, detail and goal oriented, able to work both independently and in teams, and will possess excellent organizational, communication, and analytical skills. 

Please contact Cigall Kadoch, Ph.D., directly at cigall_kadoch@dfci.harvard.edu for more information if interested (along with CV/resume), and please copy Dr. Kadoch’s assistant, Ms. Kristen Applegate, at kadochoffice@gmail.com. We will hire for this position(s) on a rolling basis over the coming months with target start date of May-July 2026, and will close the position once new hires have been confirmed. 

For more information about our laboratory, please see the (to be updated) Kadoch Lab website at http://www.kadochlab.org , our recent publications (https://www.ncbi.nlm.nih.gov/pubmed/?term=kadoch+c), and news via our X handles, @kadochlab, and @ckadoch.

Research Associate/Technician

Dana-Farber Cancer Institute, Kadoch Laboratory

Dr. Shany Koren-Hauer, Instructor and Sidney Farber Scholar in the Kadoch Laboratory at the Dana-Farber Cancer Institute, is seeking a highly qualified post-baccalaureate Technician to work directly with her and our vibrant research team, which is focused on epigenetics, chromatin regulation, cell biology, biochemistry, and cancer biology. This is a unique opportunity for students who plan to pursue either PhD, MD, or combined MD/PhD programs as their next step.

The Technician will work primarily with Dr. Koren-Hauer on defined research projects while being fully integrated into the Kadoch Laboratory’s infrastructure and scientific training environment, with additional mentorship and collaboration opportunities with Dr. Cigall Kadoch and other laboratory members.

The successful applicant will have focused prior laboratory research experience (i.e. 1-2 years during undergraduate/summers) as well as undergraduate coursework in molecular biology and will be able to work both independently and in teams.

This position is for students with two years of availability and who will be applying to graduate and/or medical school for entry in Fall of 2028. 

If interested, please contact Dr. Shany Koren-Hauer directly at shany_koren-hauer@dfci.harvard.edu for more information, and please include your CV or resume. 

For more information about our laboratory, please see the Kadoch Lab website at http://www.kadochlab.org, our recent publications (https://www.ncbi.nlm.nih.gov/pubmed/?term=kadoch+c), and news via our X handles, @kadochlab, and @ckadoch.