Kirstin Meyer

Kirstin Meyer, Ph.D.

Assistant Professor of Molecular, Cellular & Developmental Biology

Biography

Kirstin Meyer is an Assistant Professor at Yale University in the Department of Molecular, Cellular, and Developmental Biology and a member of the Systems Biology Institute. She received her doctorate from the Max Planck Institute for Molecular Cell Biology and Genetics and the Technical University Dresden in Germany, where she worked on organ size control during liver regeneration. In her postdoctoral work in Orion Weiner’s lab at the University of California San Francisco, she studied the logic of temporal information decoding for gene regulation and stem cell fate. In 2024, she started at Yale, where her lab seeks to understand the molecular mechanisms of emergent gene regulatory behavior. Her research focuses on the role of chromatin biophysics for temporal signal decoding and mechanosensing in the context of embryonic cell fate specification.

Research

Our lab seeks to understand the molecular mechanisms of emergent gene regulatory behavior. How do gene regulatory circuits sense, process, and memorize information to drive cell fate decisions during embryonic development? We are particularly interested in the role of chromatin biophysics in transcriptional regulation and study how biophysical features of transcriptional condensates complement genetic and biochemical signaling codes to regulate gene activation. Toward this end, we leverage synthetic (e.g., optogenetics) and high-resolution imaging approaches to probe, control, and engineer molecular logic circuits underlying cellular decision-making. Our long-term goal is to leverage this understanding for the rational control of stem cell fate.

Contact Info

kirstin.meyer@yale.edu

+1 (203)-737-3255

Yale Science Building, Room 434

Systems Biology Institute, ITSC 122

 

Administrative Support: 

Lisa Epifano