Research

The Department of Molecular, Cellular and Developmental Biology at Yale is a multi-disciplinary group of investigators committed to understanding the cellular, genetic and molecular basis of a diverse range of biological processes. The Department is based on the understanding that the solution to complex biological problems requires the integration of individuals with a common goal but differing expertise.  Several faculty employ computational methods and engage in interdisciplinary collaborations.

Biochemistry, Molecular Biology & Chemical Biology

  • Post-translational RNA processing
  • Non-coding RNA discovery
  • Ubiquitinization
  • Chemical protein manipulation
  • Molecular analysis of natural products
Biotechnology

  • Functional genomics using ribonuclease P
  • Creating new enzymes and genetic sensors
  • Development of pharmaceutical classes
  • Genome editing
  • Agribiotechnology
Cellular and Developmental Biology

  • Stem Cell Biology
  • Cytoskeletal dynamics and function
  • Pattern formation
  • Signal Transduction mechanisms
  • Tumorigenesis
Genetics

  • Molecular basis of olfaction
  • Transposons
  • Gene networks
  • microRNAs
  • Enzymatic DNA
Neurobiology

  • Neural computations in sensorimotor functions
  • Molecular dynamics of axon growth
  • Neural crest development
  • Neuromuscular development
  • Neural stem cells
Plant Sciences

  • Innate immunity and chemical defenses
  • Circadian Rhythm
  • Pattern formation
  • Leaf Development
  • Light triggered regulation of growth